O uso medicinal da Cannabis no controle da dor crônica não oncológica: uma revisão narrativa
DOI:
https://doi.org/10.5712/rbmfc21(48)4162Palavras-chave:
Cannabis, Dor crônica, Medicina Familiar e Comunitária, Cuidados primários de saúde, Canabinoides.Resumo
O uso terapêutico da Cannabis tem sido debatido mundialmente, com crescente produção de evidências e avanços regulatórios. No contexto da Atenção Primária à Saúde (APS), seu uso ainda é pouco explorado, apesar da relevância da dor crônica como queixa frequente. Objetivos: O objetivo deste estudo foi analisar o estado da arte do uso medicinal de extratos de Cannabis, com foco na sua aplicação na dor crônica e no papel estratégico do médico de família e comunidade em sua prescrição. Métodos: Trata-se de uma revisão narrativa da literatura, com buscas nas bases United States National Library of Medicine (PubMed), Literatura Latino- Americana e do Caribe em Ciências da Saúde (LILACS), Embase e Scientific Electronic Library Online (SciELO). Foram incluídos artigos científicos nos idiomas português, inglês e espanhol. Resultados: Os estudos analisados mostram que os canabinoides atuam em receptores do sistema endocanabinoide modulando a percepção da dor. Os efeitos adversos mais comuns incluem sonolência, boca seca e alterações cognitivas leves. Há evidências promissoras quanto à redução do uso de opioides e psicofármacos em pacientes que fazem uso terapêutico da Cannabis, embora persistam lacunas sobre segurança e eficácia em longo prazo, especialmente no contexto da APS. Conclusões: A literatura consultada sugere que o uso da Cannabis possa representar uma alternativa terapêutica viável para o manejo da dor crônica, com potencial para reduzir o uso de psicofármacos. Contudo, são necessários diretrizes específicas, capacitação profissional e mais estudos clínicos no âmbito da APS.
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Copyright (c) 2026 Rômulo Elísio Resende do Amaral, Mayra Gabriela Machado de Souza, Vágner Reis Batista
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